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Detection of CYP2C19 Genetic Variants in Malaysian Orang Asli from Massively Parallel Sequencing Data

The human cytochrome P450 (CYP) is a superfamily of enzymes that have been a focus in research for decades due to their prominent role in drug metabolism. CYP2C is one of the major subfamilies which metabolize more than 10% of all clinically used drugs. In the context of CYP2C19, several key genetic...

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Detalles Bibliográficos
Autores principales:	Ang, Geik Yong, Yu, Choo Yee, Subramaniam, Vinothini, Abdul Khalid, Mohd Ikhmal Hanif, Tuan Abdu Aziz, Tuan Azlin, Johari James, Richard, Ahmad, Aminuddin, Abdul Rahman, Thuhairah, Mohd Nor, Fadzilah, Ismail, Adzrool Idzwan, Md. Isa, Kamarudzaman, Salleh, Hood, Teh, Lay Kek, Salleh, Mohd Zaki
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5087908/ https://www.ncbi.nlm.nih.gov/pubmed/27798644 http://dx.doi.org/10.1371/journal.pone.0164169

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