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DNA Methylation of PITX2 and PANCR Is Prognostic for Overall Survival in Patients with Resected Adenocarcinomas of the Biliary Tract
Biliary tract cancers (BTC) are rare but highly aggressive malignant epithelial tumors. In order to improve the outcome in this lethal disease, novel biomarkers for diagnosis, prognosis, and therapy response prediction are urgently needed. DNA promoter methylation of PITX2 variants (PITX2ab, PITX2c)...
Autores principales: | Uhl, Barbara, Dietrich, Dimo, Branchi, Vittorio, Semaan, Alexander, Schaefer, Pauline, Gevensleben, Heidrun, Rostamzadeh, Babak, Lingohr, Philipp, Schäfer, Nico, Kalff, Jörg C., Kristiansen, Glen, Matthaei, Hanno |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5087948/ https://www.ncbi.nlm.nih.gov/pubmed/27798672 http://dx.doi.org/10.1371/journal.pone.0165769 |
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