Selection of antigenically advanced variants of seasonal influenza viruses

Influenza viruses mutate frequently, necessitating constant updates of vaccine viruses. To establish experimental approaches that may complement the current vaccine strain selection process, we selected antigenic variants from human H1N1 and H3N2 influenza virus libraries possessing random mutations...

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Detalles Bibliográficos
Autores principales: Li, Chengjun, Hatta, Masato, Burke, David F., Ping, Jihui, Zhang, Ying, Ozawa, Makoto, Taft, Andrew S., Das, Subash C., Hanson, Anthony P., Song, Jiasheng, Imai, Masaki, Wilker, Peter R., Watanabe, Tokiko, Watanabe, Shinji, Ito, Mutsumi, Iwatsuki-Horimoto, Kiyoko, Russell, Colin A., James, Sarah L., Skepner, Eugene, Maher, Eileen A., Neumann, Gabriele, Klimov, Alexander I., Kelso, Anne, McCauley, John, Wang, Dayan, Shu, Yuelong, Odagiri, Takato, Tashiro, Masato, Xu, Xiyan, Wentworth, David E., Katz, Jacqueline M., Cox, Nancy J., Smith, Derek J., Kawaoka, Yoshihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5087998/
https://www.ncbi.nlm.nih.gov/pubmed/27572841
http://dx.doi.org/10.1038/nmicrobiol.2016.58

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