Identification of Optimal Insertion Site in Recombinant Newcastle Disease Virus (rNDV) Vector Expressing Foreign Gene to Enhance Its Anti-Tumor Effect

Recombinant Newcastle disease virus (rNDV) is tumor selective and intrinsically oncolytic, which has been developed as a vector to express exogenous genes to enhance its oncolytic efficacy. Our previous studies found that insertion sites of foreign gene in rNDV vector affected its expression and ant...

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Detalles Bibliográficos
Autores principales: Pan, Ziye, He, Jinjiao, Rasoul, Lubna M., Liu, Yunye, Che, Ruixiang, Ding, Yun, Guo, Xiaocheng, Yang, Jiarui, Zou, Dehua, Zhang, Hua, Li, Deshan, Cao, Hongwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5087999/
https://www.ncbi.nlm.nih.gov/pubmed/27736965
http://dx.doi.org/10.1371/journal.pone.0164723

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