Early Growth and Neurologic Outcomes of Infants with Probable Congenital Zika Virus Syndrome

We report the early growth and neurologic findings of 48 infants in Brazil diagnosed with probable congenital Zika virus syndrome and followed to age 1–8 months. Most of these infants had microcephaly (86.7%) and craniofacial disproportion (95.8%). The clinical pattern included poor head growth with...

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Detalles Bibliográficos
Autores principales: Moura da Silva, Antonio Augusto, Ganz, Jucelia Sousa Santos, Sousa, Patricia da Silva, Doriqui, Maria Juliana Rodvalho, Ribeiro, Marizelia Rodrigues Costa, Branco, Maria dos Remédios Freitas Carvalho, Queiroz, Rejane Christine de Sousa, Pacheco, Maria de Jesus Torres, Vieira da Costa, Flavia Regina, Silva, Francelena de Sousa, Simões, Vanda Maria Ferreira, Pacheco, Marcos Antonio Barbosa, Lamy-Filho, Fernando, Lamy, Zeni Carvalho, Soares de Britto e Alves, Maria Teresa Seabra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2016
Materias:
Dispatch
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5088045/
https://www.ncbi.nlm.nih.gov/pubmed/27767931
http://dx.doi.org/10.3201/eid2211.160956
Descripción
Sumario:We report the early growth and neurologic findings of 48 infants in Brazil diagnosed with probable congenital Zika virus syndrome and followed to age 1–8 months. Most of these infants had microcephaly (86.7%) and craniofacial disproportion (95.8%). The clinical pattern included poor head growth with increasingly negative z-scores, pyramidal/extrapyramidal symptoms, and epilepsy.

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