Cargando…

The transition of smooth muscle cells from a contractile to a migratory, phagocytic phenotype: direct demonstration of phenotypic modulation

KEY POINTS: Smooth muscle cell (SMC) phenotypic conversion from a contractile to a migratory phenotype is proposed to underlie cardiovascular disease but its contribution to vascular remodelling and even its existence have recently been questioned. Tracking the fate of individual SMCs is difficult a...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sandison, Mairi E., Dempster, John, McCarron, John G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2016
Materias:	Cardiovascular
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5088226/ https://www.ncbi.nlm.nih.gov/pubmed/27393389 http://dx.doi.org/10.1113/JP272729

Ejemplares similares

Caveolin-3 Promotes a Vascular Smooth Muscle Contractile Phenotype
por: Gutierrez-Pajares, Jorge L., et al.
Publicado: (2015)

Examining the Role of Mitochondria in Ca(2+) Signaling in Native Vascular Smooth Muscle
por: McCarron, John G, et al.
Publicado: (2013)

Age decreases mitochondrial motility and increases mitochondrial size in vascular smooth muscle
por: Chalmers, Susan, et al.
Publicado: (2016)

From Structure to Function: Mitochondrial Morphology, Motion and Shaping in Vascular Smooth Muscle
por: McCarron, John G., et al.
Publicado: (2013)

Microdomains of muscarinic acetylcholine and Ins(1,4,5)P(3) receptors create ‘Ins(1,4,5)P(3) junctions’ and sites of Ca(2+) wave initiation in smooth muscle
por: Olson, Marnie L., et al.
Publicado: (2012)

Large-conductance Ca(2 +)-activated K(+) channel β1-subunit maintains the contractile phenotype of vascular smooth muscle cells
por: Wang, Meili, et al.
Publicado: (2022)

Dual effect of quercetin on rat isolated portal vein smooth muscle contractility
por: Chiwororo, Witness DH, et al.
Publicado: (2010)

Upregulation of Calcium Homeostasis Modulators in Contractile-To-Proliferative Phenotypical Transition of Pulmonary Arterial Smooth Muscle Cells
por: Rodriguez, Marisela, et al.
Publicado: (2021)

Caveolin-1 is required for contractile phenotype expression by airway smooth muscle cells
por: Gosens, Reinoud, et al.
Publicado: (2011)

Age-dependent phenotypic modulation of smooth muscle cells in the normal ascending aorta
por: Balint, Brittany, et al.
Publicado: (2023)

Phenotypic plasticity of vascular smooth muscle cells in vascular calcification: Role of mitochondria
por: Liu, Yan Zhong, et al.
Publicado: (2022)

Alterations in the contractile phenotype of the bladder: lessons for understanding physiological and pathological remodelling of smooth muscle
por: Zderic, Stephen A, et al.
Publicado: (2012)

Smooth muscle phenotype in aortic diseases: Are there other histopathological markers besides contractile myofibrils?
por: Tonar, Zbynek
Publicado: (2018)

Long non-coding RNAs: Modulators of phenotypic transformation in vascular smooth muscle cells
por: Lu, Bing-Han, et al.
Publicado: (2022)

PRDX2 Protects Against Atherosclerosis by Regulating the Phenotype and Function of the Vascular Smooth Muscle Cell
por: Li, Jing, et al.
Publicado: (2021)

The molecular and functional phenotype of glomerular podocytes reveals key features of contractile smooth muscle cells
por: Saleem, Moin A., et al.
Publicado: (2008)

Close relation of arterial ICC-like cells to the contractile phenotype of vascular smooth muscle cell
por: Pucovský, Vladimír, et al.
Publicado: (2007)

Photoelasticity-based evaluation of cellular contractile force for phenotypic discrimination of vascular smooth muscle cells
por: Sugita, Shukei, et al.
Publicado: (2019)

The Loss of Polysialic Acid Impairs the Contractile Phenotype of Peritubular Smooth Muscle Cells in the Postnatal Testis
por: Hachem, Nadim E., et al.
Publicado: (2021)

Contractile effect of Sclerocarya birrea (A Rich) Hochst (Anacardiaceae) (Marula) leaf aqueous extract on rat and rabbit isolated vascular smooth muscles
por: Mawoza, Tariro, et al.
Publicado: (2012)

Insulin Resistance Promotes the Formation of Aortic Dissection by Inducing the Phenotypic Switch of Vascular Smooth Muscle Cells
por: Zheng, Hui, et al.
Publicado: (2022)

Dynamics and Functional Interplay of Nonhistone Lysine Crotonylome and Ubiquitylome in Vascular Smooth Muscle Cell Phenotypic Remodeling
por: Cao, Shan-Hu, et al.
Publicado: (2022)

Acetylcholine released by endothelial cells facilitates flow‐mediated dilatation
por: Wilson, Calum, et al.
Publicado: (2016)

Characterization of Carotid Smooth Muscle Cells during Phenotypic Transition
por: Goikuria, Haize, et al.
Publicado: (2018)

Apelin is expressed in intimal smooth muscle cells and promotes their phenotypic transition
por: Cardoso Dos Santos, Luís Miguel, et al.
Publicado: (2023)

Direct optogenetic stimulation of smooth muscle cells to control gastric contractility
por: Vogt, Markus, et al.
Publicado: (2021)

Receptor for Advanced Glycation End-Products Signaling Interferes with the Vascular Smooth Muscle Cell Contractile Phenotype and Function
por: Simard, Elie, et al.
Publicado: (2015)

Apolipoprotein E (ApoE) Rescues the Contractile Smooth Muscle Cell Phenotype in Popliteal Artery Aneurysm Disease
por: Pauli, Jessica, et al.
Publicado: (2023)

Cell Phenotype Transitions in Cardiovascular Calcification
por: Hortells, Luis, et al.
Publicado: (2018)

The Etiology and Molecular Mechanism Underlying Smooth Muscle Phenotype Switching in Intimal Hyperplasia of Vein Graft and the Regulatory Role of microRNAs
por: Zhang, Dengshen, et al.
Publicado: (2022)

Rivaroxaban Suppresses Atherosclerosis by Inhibiting FXa-Induced Macrophage M1 Polarization-Mediated Phenotypic Conversion of Vascular Smooth Muscle Cells
por: Ma, Yanpeng, et al.
Publicado: (2021)

Vascular smooth muscle cell phenotypic transition regulates gap junctions of cardiomyocyte
por: Zhou, En, et al.
Publicado: (2020)

Exosomes: mediators regulating the phenotypic transition of vascular smooth muscle cells in atherosclerosis
por: Yao, Jiali, et al.
Publicado: (2022)

ULTRASTRUCTURAL STUDIES ON THE CONTRACTILE MECHANISM OF SMOOTH MUSCLE
por: Kelly, Robert E., et al.
Publicado: (1969)

Ghrelin, not corticosterone, is associated with transitioning of phenotypic states in a migratory Galliform
por: Marasco, Valeria, et al.
Publicado: (2023)

The cytoskeletal and contractile apparatus of smooth muscle: contraction bands and segmentation of the contractile elements
Publicado: (1990)

Airway disease phenotypes in animal models of cystic fibrosis
por: McCarron, Alexandra, et al.
Publicado: (2018)

Deciphering the Intercellular Communication Between Immune Cells and Altered Vascular Smooth Muscle Cell Phenotypes in Aortic Aneurysm From Single-Cell Transcriptome Data
por: Cao, Genmao, et al.
Publicado: (2022)

Synthesis of an azido-tagged low affinity ratiometric calcium sensor
por: Caldwell, Stuart T., et al.
Publicado: (2015)

Effects of 17β-oestradiol on rat detrusor smooth muscle contractility
por: Valeri, Aurora, et al.
Publicado: (2009)

Cannot write session to /tmp/vufind_sessions/sess_he2pcojko81okvigm67537bv7t