Cargando…

Melatoninergic System in Parkinson's Disease: From Neuroprotection to the Management of Motor and Nonmotor Symptoms

Melatonin is synthesized by several tissues besides the pineal gland, and beyond its regulatory effects in light-dark cycle, melatonin is a hormone with neuroprotective, anti-inflammatory, and antioxidant properties. Melatonin acts as a free-radical scavenger, reducing reactive species and improving...

Descripción completa

Detalles Bibliográficos
Autores principales:	Mack, Josiel Mileno, Schamne, Marissa Giovanna, Sampaio, Tuane Bazanella, Pértile, Renata Aparecida Nedel, Fernandes, Pedro Augusto Carlos Magno, Markus, Regina P., Prediger, Rui Daniel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2016
Materias:	Review Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5088323/ https://www.ncbi.nlm.nih.gov/pubmed/27829983 http://dx.doi.org/10.1155/2016/3472032

Ejemplares similares

Role of Prefrontal Cortex on Recognition Memory Deficits in Rats following 6-OHDA-Induced Locus Coeruleus Lesion
por: Sampaio, Tuane Bazanella, et al.
Publicado: (2020)

Synthetic Melatoninergic Ligands: Achievements and Prospects
por: Kostiuk, N. V., et al.
Publicado: (2014)

Local Melatoninergic System as the Protector of Skin Integrity
por: Slominski, Andrzej T., et al.
Publicado: (2014)

The Role of the Melatoninergic System in Light-Entrained Behavior of Mice
por: Pfeffer, Martina, et al.
Publicado: (2017)

A Topical Formulation of Melatoninergic Compounds Exerts Strong Hypotensive and Neuroprotective Effects in a Rat Model of Hypertensive Glaucoma
por: Dal Monte, Massimo, et al.
Publicado: (2020)

Novel Conformationally Constrained Analogues of Agomelatine as New Melatoninergic Ligands
por: Rami, Marouan, et al.
Publicado: (2012)

Temporal expression patterns of the melatoninergic system in the human thymus of children
por: Cruz-Chamorro, Ivan, et al.
Publicado: (2019)

Characterization of the Mel1c melatoninergic receptor in platypus (Ornithorhynchus anatinus)
por: Gautier, Célia, et al.
Publicado: (2018)

Neurotrophic factors in Alzheimer's and Parkinson's diseases: implications for pathogenesis and therapy
por: Sampaio, Tuane Bazanella, et al.
Publicado: (2017)

Mindfulness for Motor and Nonmotor Dysfunctions in Parkinson's Disease
por: Dissanayaka, Nadeeka N. W., et al.
Publicado: (2016)

Synthesis and Functional Characterization of Substituted Isoquinolinones as MT(2)-Selective Melatoninergic Ligands
por: Hu, Yueqing, et al.
Publicado: (2014)

Update on treatments for nonmotor symptoms of Parkinson's disease—an evidence‐based medicine review
por: Seppi, Klaus, et al.
Publicado: (2019)

Effect of Exercise on Motor and Nonmotor Symptoms of Parkinson's Disease
por: Dashtipour, Khashayar, et al.
Publicado: (2015)

The Role of the Melatoninergic System in Circadian and Seasonal Rhythms—Insights From Different Mouse Strains
por: Pfeffer, Martina, et al.
Publicado: (2022)

Synthesis and Fluorescence Properties of 4-Cyano and 4-Formyl Melatonin as Putative Melatoninergic Ligands
por: Bartolucci, Silvia, et al.
Publicado: (2023)

Nonmotor Symptoms of Parkinson's Disease
por: Rektorova, Irena, et al.
Publicado: (2011)

Nonmotor Symptoms of Parkinson's Disease
por: Wu, Shey-Lin, et al.
Publicado: (2017)

Progression of Nonmotor Symptoms in Parkinson's Disease by Sex and Motor Laterality
por: Kurlawala, Zimple, et al.
Publicado: (2021)

Stability of motor-nonmotor subtype in early-stage Parkinson’s disease
por: Xiao, Yi, et al.
Publicado: (2022)

New approaches in the management of insomnia: weighing the advantages of prolonged-release melatonin and synthetic melatoninergic agonists
por: Hardeland, Rüdiger
Publicado: (2009)

Ceruloplasmin in Parkinson's disease and the nonmotor symptoms
por: Zhao, Xuemei, et al.
Publicado: (2018)

Nonmotor symptoms in spinocerebellar ataxias (SCAs)
por: Moro, Adriana, et al.
Publicado: (2019)

Nonmotor Symptoms in Dystonia: Pathophysiological Implications
por: Mishra, Anumeha, et al.
Publicado: (2020)

Motor and nonmotor complications in Parkinson’s disease: an argument for continuous drug delivery?
por: Chaudhuri, K. Ray, et al.
Publicado: (2013)

Molecular docking studies for the identification of novel melatoninergic inhibitors for acetylserotonin-O-methyltransferase using different docking routines
por: Azam, Syed Sikander, et al.
Publicado: (2013)

Nonmotor Symptoms in Patients with PARK2 Mutations
por: Yoritaka, Asako, et al.
Publicado: (2011)

Dopamine-Induced Nonmotor Symptoms of Parkinson's Disease
por: Park, Ariane, et al.
Publicado: (2011)

Neuropathology and Neurochemistry of Nonmotor Symptoms in Parkinson's Disease
por: Ferrer, Isidro
Publicado: (2011)

Evaluation of Nonmotor Symptoms in Diagnosis of Parkinsonism and Tremor
por: Evans, Andrew H., et al.
Publicado: (2016)

Characteristics of Nonmotor Symptoms in Progressive Supranuclear Palsy
por: Ou, Ruwei, et al.
Publicado: (2016)

Relationship between Motor and Nonmotor Symptoms and Quality of Life in Patients with Parkinson’s Disease
por: Candel-Parra, Eduardo, et al.
Publicado: (2021)

Delineating nonmotor symptoms in early Parkinson's disease and first‐degree relatives
por: Baig, Fahd, et al.
Publicado: (2015)

Prenatal hypoxia alters the early ontogeny of dopamine neurons
por: Brandon, Anastasia, et al.
Publicado: (2022)

Brain Connectomics' Modification to Clarify Motor and Nonmotor Features of Myotonic Dystrophy Type 1
por: Serra, Laura, et al.
Publicado: (2016)

Real‐World Nonmotor Changes in Patients with Parkinson's Disease and Motor Fluctuations: J‐FIRST
por: Watanabe, Hirohisa, et al.
Publicado: (2020)

Modular output circuits of the fastigial nucleus for diverse motor and nonmotor functions of the cerebellar vermis
por: Fujita, Hirofumi, et al.
Publicado: (2020)

Mesenchymal stem cells in Parkinson’s disease: Motor and nonmotor symptoms in the early posttransplant period
por: Boika, Aliaksandr, et al.
Publicado: (2020)

Do Benzodiazepines Impair Motor and Nonmotor Symptoms in a Sample of Parkinson’s Disease Patients?
por: Gaztanaga, Wendy, et al.
Publicado: (2021)

Staging Parkinson's Disease Combining Motor and Nonmotor Symptoms Correlates with Disability and Quality of Life
por: Santos García, D., et al.
Publicado: (2021)

Nonmotor Symptoms in a Malaysian Parkinson's Disease Population
por: Azmin, Shahrul, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_7aoll4tk83gq9r9h5l924tpqvq