The polymyxin B-induced transcriptomic response of a clinical, multidrug-resistant Klebsiella pneumoniae involves multiple regulatory elements and intracellular targets

BACKGROUND: The emergence of multidrug-resistant Klebsiella pneumoniae is a major public health concern. Many K. pneumoniae infections can only be treated when resorting to last-line drugs such as polymyxin B (PB). However, resistance to this antibiotic is also observed, although insufficient inform...

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Detalles Bibliográficos
Autores principales: Ramos, Pablo Ivan Pereira, Custódio, Márlon Grégori Flores, Quispe Saji, Guadalupe del Rosario, Cardoso, Thiago, da Silva, Gisele Lucchetti, Braun, Graziela, Martins, Willames M. B. S., Girardello, Raquel, de Vasconcelos, Ana Tereza Ribeiro, Fernández, Elmer, Gales, Ana Cristina, Nicolás, Marisa Fabiana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5088521/
https://www.ncbi.nlm.nih.gov/pubmed/27801293
http://dx.doi.org/10.1186/s12864-016-3070-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5088521/
https://www.ncbi.nlm.nih.gov/pubmed/27801293
http://dx.doi.org/10.1186/s12864-016-3070-y

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