An Autopsy Case of Lepidic Pulmonary Metastasis from Cholangiocarcinoma

We herein report the first case of pulmonary metastasis with lepidic growth that originated from cholangiocarcinoma. A 77-year-old man was admitted to our hospital due to exertional dyspnea and liver dysfunction. Computed tomography showed widespread infiltration and a ground-glass opacity in the lu...

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Detalles Bibliográficos
Autores principales: Nagayoshi, Yohsuke, Yamamoto, Kazuko, Hashimoto, Satoru, Hisatomi, Keiko, Doi, Seiji, Nagashima, Seiji, Kurohama, Hirokazu, Ito, Masahiro, Takazono, Takahiro, Nakamura, Shigeki, Miyazaki, Taiga, Kohno, Shigeru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2016
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5088548/
https://www.ncbi.nlm.nih.gov/pubmed/27725547
Descripción
Sumario:We herein report the first case of pulmonary metastasis with lepidic growth that originated from cholangiocarcinoma. A 77-year-old man was admitted to our hospital due to exertional dyspnea and liver dysfunction. Computed tomography showed widespread infiltration and a ground-glass opacity in the lung and dilation of the intrahepatic bile duct. The pulmonary lesion progressed rapidly, and the patient died of respiratory failure. Cholangiocarcinoma and lepidic pulmonary metastasis were pathologically diagnosed by an autopsy. Lepidic pulmonary growth is an atypical pattern of metastasis, and immunopathological staining is useful to distinguish pulmonary metastasis from extrapulmonary cancer and primary pulmonary adenocarcinoma.

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