Binding of nuclear factor κB to noncanonical consensus sites reveals its multimodal role during the early inflammatory response

Mammalian cells have developed intricate mechanisms to interpret, integrate, and respond to extracellular stimuli. For example, tumor necrosis factor (TNF) rapidly activates proinflammatory genes, but our understanding of how this occurs against the ongoing transcriptional program of the cell is far...

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Detalles Bibliográficos
Autores principales: Kolovos, Petros, Georgomanolis, Theodore, Koeferle, Anna, Larkin, Joshua D., Brant, Lilija, Nikolicć, Miloš, Gusmao, Eduardo G., Zirkel, Anne, Knoch, Tobias A., van Ijcken, Wilfred F., Cook, Peter R., Costa, Ivan G., Grosveld, Frank G., Papantonis, Argyris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5088591/
https://www.ncbi.nlm.nih.gov/pubmed/27633323
http://dx.doi.org/10.1101/gr.210005.116

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