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An integrated metagenomics pipeline for strain profiling reveals novel patterns of bacterial transmission and biogeography

We present the Metagenomic Intra-species Diversity Analysis System (MIDAS), which is an integrated computational pipeline for quantifying bacterial species abundance and strain-level genomic variation, including gene content and single-nucleotide polymorphisms (SNPs), from shotgun metagenomes. Our m...

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Detalles Bibliográficos
Autores principales: Nayfach, Stephen, Rodriguez-Mueller, Beltran, Garud, Nandita, Pollard, Katherine S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5088602/
https://www.ncbi.nlm.nih.gov/pubmed/27803195
http://dx.doi.org/10.1101/gr.201863.115