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A retrospective study detects a novel variant of porcine epidemic diarrhea virus in England in archived material from the year 2000

Outbreaks of porcine epidemic diarrhea (PED) were first recorded in England in the 1970s and continued to be confirmed until 2002. Retrospective analysis of archived material from one of the last confirmed cases in England in the year 2000 demonstrates the previous existence of a very diverse PED vi...

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Detalles Bibliográficos
Autores principales: Steinbach, Falko, Dastjerdi, Akbar, Peake, Julie, La Rocca, S. Anna, Tobin, Frank P., Frossard, Jean-Pierre, Williamson, Susanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5088618/
https://www.ncbi.nlm.nih.gov/pubmed/27812401
http://dx.doi.org/10.7717/peerj.2564
Descripción
Sumario:Outbreaks of porcine epidemic diarrhea (PED) were first recorded in England in the 1970s and continued to be confirmed until 2002. Retrospective analysis of archived material from one of the last confirmed cases in England in the year 2000 demonstrates the previous existence of a very diverse PED virus strain. Following the outbreaks of PED in North America in 2013, there has been renewed interest in phylogenetic analysis of sequences from PEDV strains worldwide. There is a gap in the available sequence data between the mid 1980s and the mid 2000s. This work is an example of how this gap can be at least partially filled by the examination of archived material.