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Detection of anti-drug antibodies using a bridging ELISA compared with radioimmunoassay in adalimumab-treated rheumatoid arthritis patients with random drug levels

Objective. To determine the concordance between RIA and bridging ELISA at detecting anti-drug antibodies (ADAbs) in the context of random adalimumab levels and investigate the additional clinical utility of detecting ADAbs in RA patients who test ADAb positive by RIA and negative by ELISA. Methods....

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Detalles Bibliográficos
Autores principales: Jani, Meghna, Isaacs, John D., Morgan, Ann W., Wilson, Anthony G., Plant, Darren, Hyrich, Kimme L., Chinoy, Hector, Barton, Anne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5088626/
https://www.ncbi.nlm.nih.gov/pubmed/27565176
http://dx.doi.org/10.1093/rheumatology/kew299