Integrative network analysis of nineteen brain regions identifies molecular signatures and networks underlying selective regional vulnerability to Alzheimer’s disease

BACKGROUND: Alzheimer’s disease (AD) is the most common form of dementia, characterized by progressive cognitive impairment and neurodegeneration. However, despite extensive clinical and genomic studies, the molecular basis of AD development and progression remains elusive. METHODS: To elucidate mol...

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Detalles Bibliográficos
Autores principales: Wang, Minghui, Roussos, Panos, McKenzie, Andrew, Zhou, Xianxiao, Kajiwara, Yuji, Brennand, Kristen J., De Luca, Gabriele C., Crary, John F., Casaccia, Patrizia, Buxbaum, Joseph D., Ehrlich, Michelle, Gandy, Sam, Goate, Alison, Katsel, Pavel, Schadt, Eric, Haroutunian, Vahram, Zhang, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5088659/
https://www.ncbi.nlm.nih.gov/pubmed/27799057
http://dx.doi.org/10.1186/s13073-016-0355-3

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