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β-Catenin/CBP–Dependent Signaling Regulates TGF-β–Induced Epithelial to Mesenchymal Transition of Lens Epithelial Cells

PURPOSE: Transforming growth factor-β–induced epithelial–mesenchymal transition (EMT) is one of the main causes of posterior capsular opacification (PCO) or secondary cataract; however, the signaling events involved in TGF-β–induced PCO have not been fully characterized. Here, we focus on examining...

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Detalles Bibliográficos
Autores principales: Taiyab, Aftab, Korol, Anna, Deschamps, Paula A., West-Mays, Judith A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5089212/
https://www.ncbi.nlm.nih.gov/pubmed/27787561
http://dx.doi.org/10.1167/iovs.16-20162