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NLRP12 Modulates Host Defense through IL-17A-CXCL1 Axis

We used an extracellular pathogen Klebsiella pneumoniae to determine the role of NLRP12 since this bacterium is associated with devastating pulmonary infections. We found human myeloid cells (neutrophils and macrophages) and non-myeloid cells (epithelial cells) show upregulation of NLRP12 in human p...

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Detalles Bibliográficos
Autores principales:	Cai, Shanshan, Batra, Sanjay, Piero, Fabio Del, Jeyaseelan, Samithamby
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5089371/ https://www.ncbi.nlm.nih.gov/pubmed/26349659 http://dx.doi.org/10.1038/mi.2015.80

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