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E2F1 and TFDP1 Regulate PITX1 Expression in Normal and Osteoarthritic Articular Chondrocytes

We previously reported a loss-of-PITX1 expression in patients suffering of knee/hip osteoarthritis (OA). Search for the mechanism underlying this event led us to discover that PITX1 repression was triggered by the aberrant nuclear accumulation of Prohibitin (PHB1), an E2F1 co-repressor, in OA articu...

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Detalles Bibliográficos
Autores principales:	Pellicelli, Martin, Picard, Cynthia, Wang, DaShen, Lavigne, Patrick, Moreau, Alain
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5089553/ https://www.ncbi.nlm.nih.gov/pubmed/27802335 http://dx.doi.org/10.1371/journal.pone.0165951

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