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Hepatocellular carcinoma repression by TNFα‐mediated synergistic lethal effect of mitosis defect‐induced senescence and cell death sensitization

Hepatocellular carcinoma (HCC) is a cancer lacking effective therapies. Several measures have been proposed to treat HCCs, such as senescence induction, mitotic inhibition, and cell death promotion. However, data from other cancers suggest that single use of these approaches may not be effective. He...

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Detalles Bibliográficos
Autores principales: Li, Dan, Fu, Jing, Du, Min, Zhang, Haibin, Li, Lu, Cen, Jin, Li, Weiyun, Chen, Xiaotao, Lin, Yunfei, Conway, Edward M., Pikarsky, Eli, Wang, Hongyan, Pan, Guoyu, Ji, Yuan, Wang, Hong‐Yang, Hui, Lijian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5089570/
https://www.ncbi.nlm.nih.gov/pubmed/27177758
http://dx.doi.org/10.1002/hep.28637