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A BOILED‐Egg To Predict Gastrointestinal Absorption and Brain Penetration of Small Molecules
Apart from efficacy and toxicity, many drug development failures are imputable to poor pharmacokinetics and bioavailability. Gastrointestinal absorption and brain access are two pharmacokinetic behaviors crucial to estimate at various stages of the drug discovery processes. To this end, the Brain Or...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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John Wiley and Sons Inc.
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5089604/ https://www.ncbi.nlm.nih.gov/pubmed/27218427 http://dx.doi.org/10.1002/cmdc.201600182 |