Copper(I)–Phosphinite Complexes in Click Cycloadditions: Three‐Component Reactions and Preparation of 5‐Iodotriazoles

The remarkable activity displayed by copper(I)–phosphinite complexes of general formula [CuBr(L)] in two challenging cycloadditions is reported: a) the one‐pot azidonation/cycloaddition of boronic acids, NaN(3), and terminal alkynes; b) the cycloaddition of azides and iodoalkynes. These air‐stable c...

Descripción completa

Detalles Bibliográficos
Autores principales: Pérez, Juana M., Crosbie, Peter, Lal, Steven, Díez‐González, Silvia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Full Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5089671/
https://www.ncbi.nlm.nih.gov/pubmed/27840662
http://dx.doi.org/10.1002/cctc.201600234
Descripción
Sumario:The remarkable activity displayed by copper(I)–phosphinite complexes of general formula [CuBr(L)] in two challenging cycloadditions is reported: a) the one‐pot azidonation/cycloaddition of boronic acids, NaN(3), and terminal alkynes; b) the cycloaddition of azides and iodoalkynes. These air‐stable catalysts led to very good results in both cases and the expected triazoles could be isolated in pure form under ‘Click‐suitable’ conditions.

Ejemplares similares