Copper(I)–Phosphinite Complexes in Click Cycloadditions: Three‐Component Reactions and Preparation of 5‐Iodotriazoles

The remarkable activity displayed by copper(I)–phosphinite complexes of general formula [CuBr(L)] in two challenging cycloadditions is reported: a) the one‐pot azidonation/cycloaddition of boronic acids, NaN(3), and terminal alkynes; b) the cycloaddition of azides and iodoalkynes. These air‐stable c...

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Autores principales: Pérez, Juana M., Crosbie, Peter, Lal, Steven, Díez‐González, Silvia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Full Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5089671/
https://www.ncbi.nlm.nih.gov/pubmed/27840662
http://dx.doi.org/10.1002/cctc.201600234
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author Pérez, Juana M.
Crosbie, Peter
Lal, Steven
Díez‐González, Silvia
author_facet Pérez, Juana M.
Crosbie, Peter
Lal, Steven
Díez‐González, Silvia
author_sort Pérez, Juana M.
collection PubMed
description The remarkable activity displayed by copper(I)–phosphinite complexes of general formula [CuBr(L)] in two challenging cycloadditions is reported: a) the one‐pot azidonation/cycloaddition of boronic acids, NaN(3), and terminal alkynes; b) the cycloaddition of azides and iodoalkynes. These air‐stable catalysts led to very good results in both cases and the expected triazoles could be isolated in pure form under ‘Click‐suitable’ conditions.
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spelling pubmed-50896712016-11-09 Copper(I)–Phosphinite Complexes in Click Cycloadditions: Three‐Component Reactions and Preparation of 5‐Iodotriazoles Pérez, Juana M. Crosbie, Peter Lal, Steven Díez‐González, Silvia ChemCatChem Full Papers The remarkable activity displayed by copper(I)–phosphinite complexes of general formula [CuBr(L)] in two challenging cycloadditions is reported: a) the one‐pot azidonation/cycloaddition of boronic acids, NaN(3), and terminal alkynes; b) the cycloaddition of azides and iodoalkynes. These air‐stable catalysts led to very good results in both cases and the expected triazoles could be isolated in pure form under ‘Click‐suitable’ conditions. John Wiley and Sons Inc. 2016-06-13 2016-07-06 /pmc/articles/PMC5089671/ /pubmed/27840662 http://dx.doi.org/10.1002/cctc.201600234 Text en © 2016 The Authors. Published by Wiley-VCH Verlag GmbH & Co. KGaA. This is an open access article under the terms of the Creative Commons Attribution (http://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Full Papers
Pérez, Juana M.
Crosbie, Peter
Lal, Steven
Díez‐González, Silvia
Copper(I)–Phosphinite Complexes in Click Cycloadditions: Three‐Component Reactions and Preparation of 5‐Iodotriazoles
title Copper(I)–Phosphinite Complexes in Click Cycloadditions: Three‐Component Reactions and Preparation of 5‐Iodotriazoles
title_full Copper(I)–Phosphinite Complexes in Click Cycloadditions: Three‐Component Reactions and Preparation of 5‐Iodotriazoles
title_fullStr Copper(I)–Phosphinite Complexes in Click Cycloadditions: Three‐Component Reactions and Preparation of 5‐Iodotriazoles
title_full_unstemmed Copper(I)–Phosphinite Complexes in Click Cycloadditions: Three‐Component Reactions and Preparation of 5‐Iodotriazoles
title_short Copper(I)–Phosphinite Complexes in Click Cycloadditions: Three‐Component Reactions and Preparation of 5‐Iodotriazoles
title_sort copper(i)–phosphinite complexes in click cycloadditions: three‐component reactions and preparation of 5‐iodotriazoles
topic Full Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5089671/
https://www.ncbi.nlm.nih.gov/pubmed/27840662
http://dx.doi.org/10.1002/cctc.201600234
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