Cargando…

Fusion of Human Fetal Mesenchymal Stem Cells with “Degenerating” Cerebellar Neurons in Spinocerebellar Ataxia Type 1 Model Mice

Mesenchymal stem cells (MSCs) migrate to damaged tissues, where they participate in tissue repair. Human fetal MSCs (hfMSCs), compared with adult MSCs, have higher proliferation rates, a greater differentiation capacity and longer telomeres with reduced senescence. Therefore, transplantation of qual...

Descripción completa

Detalles Bibliográficos
Autores principales:	Huda, Fathul, Fan, Yiping, Suzuki, Mamiko, Konno, Ayumu, Matsuzaki, Yasunori, Takahashi, Nobutaka, Chan, Jerry K. Y., Hirai, Hirokazu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5089746/ https://www.ncbi.nlm.nih.gov/pubmed/27802273 http://dx.doi.org/10.1371/journal.pone.0164202

Ejemplares similares

Distinct transduction profiles in the CNS via three injection routes of AAV9 and the application to generation of a neurodegenerative mouse model
por: Huda, Fathul, et al.
Publicado: (2014)

Aberrant Cerebellar Circuitry in the Spinocerebellar Ataxias
por: Robinson, Katherine J., et al.
Publicado: (2020)

Unique degeneration signatures in the cerebellar cortex for spinocerebellar ataxias 2, 3, and 7
por: Hernandez-Castillo, Carlos R., et al.
Publicado: (2018)

Viral Vector-Based Dissection of Marmoset GFAP Promoter in Mouse and Marmoset Brains
por: Shinohara, Yoichiro, et al.
Publicado: (2016)

Protein kinase Cγ in cerebellar Purkinje cells regulates Ca(2+)-activated large-conductance K(+) channels and motor coordination
por: Watanave, Masashi, et al.
Publicado: (2022)

CAG repeat length does not associate with the rate of cerebellar degeneration in spinocerebellar ataxia type 3
por: Huang, Shang-Ran, et al.
Publicado: (2016)

Neurocognitive and cerebellar function in ADHD, autism and spinocerebellar ataxia
por: Cundari, Maurizio, et al.
Publicado: (2023)

Clinical and genetic profile in index patients with spinocerebellar ataxia type 3 in Indonesia: case report
por: Aminah, Siti, et al.
Publicado: (2021)

Minimal Purkinje Cell-Specific PCP2/L7 Promoter Virally Available for Rodents and Non-human Primates
por: Nitta, Keisuke, et al.
Publicado: (2017)

A blood-brain barrier-penetrating AAV2 mutant created by a brain microvasculature endothelial cell-targeted AAV2 variant
por: Kawabata, Hayato, et al.
Publicado: (2023)

Cerebellar Development and Circuit Maturation: A Common Framework for Spinocerebellar Ataxias
por: Binda, Francesca, et al.
Publicado: (2020)

Copy Number Variant Analysis of Spinocerebellar Ataxia Genes in a Cohort of Dutch Patients With Cerebellar Ataxia
por: Ghorbani, Fatemeh, et al.
Publicado: (2023)

Spinocerebellar Ataxia 13 Presenting with Pure Cerebellar Syndrome in a Korean Family
por: Kim, Minkyeong, et al.
Publicado: (2020)

Cerebellar developmental deficits underlie neurodegenerative disorder spinocerebellar ataxia type 23
por: Smeets, Cleo J.L.M., et al.
Publicado: (2020)

Radiological hints for differentiation of cerebellar multiple system atrophy from spinocerebellar ataxia
por: Chen, Hung-Chieh, et al.
Publicado: (2022)

An understanding of spinocerebellar ataxia
por: Ramachandra, N.B., et al.
Publicado: (2015)

Parkinsonism in Spinocerebellar Ataxia
por: Park, Hyeyoung, et al.
Publicado: (2015)

Spinocerebellar ataxia: an update
por: Sullivan, Roisin, et al.
Publicado: (2018)

4-aminopyridine reverses ataxia and cerebellar firing deficiency in a mouse model of spinocerebellar ataxia type 6
por: Jayabal, Sriram, et al.
Publicado: (2016)

Distinctive features of degenerating Purkinje cells in spinocerebellar ataxia type 31
por: Yoshida, Kunihiro, et al.
Publicado: (2014)

Cerebellar neuronal dysfunction accompanies early motor symptoms in spinocerebellar ataxia type 3
por: Mayoral-Palarz, Kristin, et al.
Publicado: (2022)

Altered H3 histone acetylation impairs high-fidelity DNA repair to promote cerebellar degeneration in spinocerebellar ataxia type 7
por: Switonski, Pawel M., et al.
Publicado: (2021)

Postural Tremor and Ataxia Progression in Spinocerebellar Ataxias
por: Gan, Shi-Rui, et al.
Publicado: (2017)

Cerebellar transcranial magnetic stimulation facilitates excitability of spinal reflex, but does not affect cerebellar inhibition and facilitation in spinocerebellar ataxia
por: Matsugi, Akiyoshi, et al.
Publicado: (2018)

Spinocerebellar ataxia type 7 without retinal degeneration: a case report.
por: Kim, Byeong-Chae, et al.
Publicado: (2002)

RNA Interference-Based Therapy for Spinocerebellar Ataxia Type 7 Retinal Degeneration
por: Ramachandran, Pavitra S., et al.
Publicado: (2014)

Spinocerebellar Ataxia Type 7 Sans Retinal Degeneration: A Phenotypic Variability
por: Mahale, Rohan R., et al.
Publicado: (2017)

Progressive degeneration in a new Drosophila model of Spinocerebellar Ataxia type 7
por: Sujkowski, Alyson L., et al.
Publicado: (2023)

Cell biology of spinocerebellar ataxia
por: Orr, Harry T.
Publicado: (2012)

Cognitive dysfunction in spinocerebellar ataxias
por: Teive, Helio Afonso Ghizoni, et al.
Publicado: (2009)

Neuroradiological Findings in the Spinocerebellar Ataxias
por: Meira, Alex Tiburtino, et al.
Publicado: (2019)

Rapid Onset of Motor Deficits in a Mouse Model of Spinocerebellar Ataxia Type 6 Precedes Late Cerebellar Degeneration(1,2,3)
por: Jayabal, Sriram, et al.
Publicado: (2015)

MRI-based cerebellar volume measurements correlate with the International Cooperative Ataxia Rating Scale score in patients with spinocerebellar degeneration or multiple system atrophy
por: Hara, Daisuke, et al.
Publicado: (2016)

Extra-Cerebellar Signs and Non-motor Features in Chinese Patients With Spinocerebellar Ataxia Type 3
por: Yuan, Xiaoqin, et al.
Publicado: (2019)

Effects of Repetitive Transcranial Magnetic Stimulation on Cerebellar Metabolism in Patients With Spinocerebellar Ataxia Type 3
por: Chen, Xin-Yuan, et al.
Publicado: (2022)

Quantitative evaluation of upper limb ataxia in spinocerebellar ataxias
por: Kishimoto, Yoshiyuki, et al.
Publicado: (2022)

Pulling complexes out of complex diseases: Spinocerebellar Ataxia 7
por: Mohan, Ryan D, et al.
Publicado: (2014)

Spinocerebellar Ataxia 12 Patients have better Quality of Life than Spinocerebellar Ataxia 1 and 2
por: Dabla, Surekha, et al.
Publicado: (2022)

Disability in cerebellar ataxia syndromes is linked to cortical degeneration
por: Conrad, Julian, et al.
Publicado: (2023)

Differences between Spinocerebellar Ataxias and Multiple System Atrophy-Cerebellar Type on Proton Magnetic Resonance Spectroscopy
por: Lirng, Jiing-Feng, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_p19g2lbsp7kmnj0q4kfa9a88e9