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Protective Effects of Essential Oils as Natural Antioxidants against Hepatotoxicity Induced by Cyclophosphamide in Mice

Clinical application of cyclophosphamide (CP) as an anticancer drug is often limited due to its toxicity. CP is metabolized mainly in the liver by cytochrome P450 system into acrolein which is the proximate toxic metabolite. Many different natural antioxidants were found to alleviate the toxic effec...

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Detalles Bibliográficos
Autores principales:	Sheweita, Salah A., El-Hosseiny, Lobna S., Nashashibi, Munther A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5089748/ https://www.ncbi.nlm.nih.gov/pubmed/27802299 http://dx.doi.org/10.1371/journal.pone.0165667

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