Cargando…

Protective Effects of Essential Oils as Natural Antioxidants against Hepatotoxicity Induced by Cyclophosphamide in Mice

Clinical application of cyclophosphamide (CP) as an anticancer drug is often limited due to its toxicity. CP is metabolized mainly in the liver by cytochrome P450 system into acrolein which is the proximate toxic metabolite. Many different natural antioxidants were found to alleviate the toxic effec...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sheweita, Salah A., El-Hosseiny, Lobna S., Nashashibi, Munther A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5089748/ https://www.ncbi.nlm.nih.gov/pubmed/27802299 http://dx.doi.org/10.1371/journal.pone.0165667

Ejemplares similares

Oxidative Stress Alleviation by Sage Essential Oil in Co-amoxiclav induced Hepatotoxicity in Rats
por: El-Hosseiny, L. S., et al.
Publicado: (2016)

In vitro evaluation of the combination between some antibiotics and essential oils of clove and rosemary against Pseudomonas aeruginosa
por: El Hosseiny, L, et al.
Publicado: (2015)

Chemical composition and protective effect of Juniperus sabina L. essential oil against CCl(4) induced hepatotoxicity
por: Abdel-Kader, Maged S., et al.
Publicado: (2019)

Protective effects of Artemisia arborescens essential oil on oestroprogestative treatment induced hepatotoxicity
por: Dhibi, Sabah, et al.
Publicado: (2015)

Potential Protective Effects of Antioxidants against Cyclophosphamide-Induced Nephrotoxicity
por: Ayza, Muluken Altaye, et al.
Publicado: (2022)

Low-dose cyclophosphamide-induced acute hepatotoxicity
por: Subramaniam, S. Ravih, et al.
Publicado: (2013)

Low-Dose Cyclophosphamide Associated With Hyponatremia and Hepatotoxicity
por: DeChiara, James R, et al.
Publicado: (2023)

Tramadol-induced hepato- and nephrotoxicity in rats: Role of Curcumin and Gallic acid as antioxidants
por: Sheweita, Salah A., et al.
Publicado: (2018)

Antioxidative and Anti-Inflammatory Protective Effects of Fucoxanthin against Paracetamol-Induced Hepatotoxicity in Rats
por: Koshak, Maimonah Fuad, et al.
Publicado: (2023)

Erectile dysfunction drugs altered the activities of antioxidant enzymes, oxidative stress and the protein expressions of some cytochrome P(450) isozymes involved in the steroidogenesis of steroid hormones
por: Sheweita, Salah A., et al.
Publicado: (2020)

Drug-Metabolizing Enzymes and Metabolic Diseases: Role of Antioxidants
por: Sheweita, Salah A., et al.
Publicado: (2016)

Upregulation of Nrf2/HO-1 Signaling and Attenuation of Oxidative Stress, Inflammation, and Cell Death Mediate the Protective Effect of Apigenin against Cyclophosphamide Hepatotoxicity
por: Al-Amarat, Wesam, et al.
Publicado: (2022)

Chitohexaose protects against acetaminophen-induced hepatotoxicity in mice
por: Barman, P K, et al.
Publicado: (2016)

Calcitriol Protects against Acetaminophen-Induced Hepatotoxicity in Mice
por: Sriphoosanaphan, Supachaya, et al.
Publicado: (2023)

Protective Effects of Evening Primrose Oil against Cyclophosphamide-Induced Biochemical, Histopathological, and Genotoxic Alterations in Mice
por: Khodeer, Dina M., et al.
Publicado: (2020)

EFFICIENCY OF BORAGE SEEDS OIL AGAINST GAMMA IRRADIATION-INDUCED HEPATOTOXICITY IN MALE RATS: POSSIBLE ANTIOXIDANT ACTIVITY
por: Khattab, Hala A.H., et al.
Publicado: (2017)

The Potential Protective Role of Naringenin against Dasatinib-Induced Hepatotoxicity
por: Alanazi, Ahmed Z., et al.
Publicado: (2023)

Protective Effect of Bergenin against Cyclophosphamide-Induced Immunosuppression by Immunomodulatory Effect and Antioxidation in Balb/c Mice
por: Qi, Qiuchen, et al.
Publicado: (2018)

Antioxidant and Protective Effects of Artemisia campestris Essential Oil Against Chlorpyrifos-Induced Kidney and Liver Injuries in Rats
por: Saoudi, Mongi, et al.
Publicado: (2021)

Carnosic acid protects against acetaminophen-induced hepatotoxicity by potentiating Nrf2-mediated antioxidant capacity in mice
por: Guo, Qi, et al.
Publicado: (2016)

Dose-Dependent Effect of Hydrogen Sulfide in Cyclophosphamide-Induced Hepatotoxicity in Rats
por: Özatik, Fikriye Yasemin, et al.
Publicado: (2023)

The hepatoprotective activity of olive oil and Nigella sativa oil against CCl(4) induced hepatotoxicity in male rats
por: Al-Seeni, Madeha N., et al.
Publicado: (2016)

Lucrative antioxidant effect of metformin against cyclophosphamide induced nephrotoxicity
por: Tohamy, Adel F., et al.
Publicado: (2021)

Hepatoprotective and Antioxidative Activities of Cornus officinalis against Acetaminophen-Induced Hepatotoxicity in Mice
por: Lee, Nam-Hun, et al.
Publicado: (2012)

Erratum to: 18β-Glycyrrhetinic acid exerts protective effects against cyclophosphamide-induced hepatotoxicity: potential role of PPARγ and Nrf2 upregulation
por: Mahmoud, Ayman M., et al.
Publicado: (2016)

Antioxidants (selenium and garlic) alleviated the adverse effects of tramadol on the reproductive system and oxidative stress markers in male rabbits
por: Sheweita, Salah A., et al.
Publicado: (2022)

Protective Effects of Fullerene C(60) Nanoparticles and Virgin Olive Oil against Genotoxicity Induced by Cyclophosphamide in Rats
por: Aly, Fayza M., et al.
Publicado: (2018)

Thymus vulgaris Essential Oil Protects Zebrafish against Cognitive Dysfunction by Regulating Cholinergic and Antioxidants Systems
por: Capatina, Luminita, et al.
Publicado: (2020)

Overexpression of Nrf2 Protects against Microcystin-Induced Hepatotoxicity in Mice
por: Lu, Yuan-Fu, et al.
Publicado: (2014)

Genistein Ameliorates Cyclophosphamide - Induced Hepatotoxicity by Modulation of Oxidative Stress and Inflammatory Mediators
por: Mansour, Dina F., et al.
Publicado: (2017)

Author Correction: Antioxidants (selenium and garlic) alleviated the adverse effects of tramadol on the reproductive system and oxidative stress markers in male rabbits
por: Sheweita, Salah A., et al.
Publicado: (2022)

Antioxidative and Energy Metabolism-Improving Effects of Maca Polysaccharide on Cyclophosphamide-Induced Hepatotoxicity Mice via Metabolomic Analysis and Keap1-Nrf2 Pathway
por: Fei, Wenting, et al.
Publicado: (2022)

Cytoprotective Antioxidant, Anti-Inflammatory, and Antifibrotic Impact of Celery Seed Oil and Manuka Honey Against Cyclophosphamide-Induced Cystitis in Rabbits
por: Mousa, Ayman M., et al.
Publicado: (2022)

Effective antioxidant, antimicrobial and anticancer activities of essential oils of horticultural aromatic crops in northern Egypt
por: Elansary, Hosam O., et al.
Publicado: (2018)

Amelioration of Prallethrin-Induced Oxidative Stress and Hepatotoxicity in Rat by the Administration of Origanum majorana Essential Oil
por: Mossa, Abdel-Tawab H., et al.
Publicado: (2013)

Antioxidant Activity of Essential Oils
por: Tit, Delia Mirela, et al.
Publicado: (2023)

Immunostimulant potential of Moringa Oleifera leaves alcoholic extract versus Oregano Essential Oil (OEO) against cyclophosphamide-induced immunosuppression in broilers chicks
por: Mohamed, Mostafa Abdelgaber, et al.
Publicado: (2023)

Protective effect of dexpanthenol against cisplatin-induced hepatotoxicity
por: Bilgic, Yilmaz, et al.
Publicado: (2018)

Protective effect of tolvaptan against cyclophosphamide‐induced nephrotoxicity in rat models
por: El‐Shabrawy, Mohamed, et al.
Publicado: (2020)

Boswellia Essential Oil: Natural Antioxidant as an Effective Antimicrobial and Anti-Inflammatory Agent
por: Obiștioiu, Diana, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_ebv5thejnsneu2k354odpd8jof