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Effect of Sodium-Glucose Co-Transporter 2 Inhibitor, Dapagliflozin, on Renal Renin-Angiotensin System in an Animal Model of Type 2 Diabetes

BACKGROUND: Renal renin-angiotensin system (RAS) activation is one of the important pathogenic mechanisms in the development of diabetic nephropathy in type 2 diabetes. The aim of this study was to investigate the effects of a sodium-glucose co-transporter 2 (SGLT-2) inhibitor, dapagliflozin, on ren...

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Detalles Bibliográficos
Autores principales: Shin, Seok Joon, Chung, Sungjin, Kim, Soo Jung, Lee, Eun-Mi, Yoo, Young-Hye, Kim, Ji-Won, Ahn, Yu-Bae, Kim, Eun-Sook, Moon, Sung-Dae, Kim, Myung-Jun, Ko, Seung-Hyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5089752/
https://www.ncbi.nlm.nih.gov/pubmed/27802313
http://dx.doi.org/10.1371/journal.pone.0165703

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