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Selective Estrogen Receptor Modulators Suppress Hif1α Protein Accumulation in Mouse Osteoclasts

Anti-bone resorptive drugs such as bisphosphonates, the anti-RANKL antibody (denosumab), or selective estrogen receptor modulators (SERMs) have been developed to treat osteoporosis. Mechanisms underlying activity of bisphosphonates or denosumab in this context are understood, while it is less clear...

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Detalles Bibliográficos
Autores principales: Morita, Mayu, Sato, Yuiko, Iwasaki, Ryotaro, Kobayashi, Tami, Watanabe, Ryuichi, Oike, Takatsugu, Miyamoto, Kana, Toyama, Yoshiaki, Matsumoto, Morio, Nakamura, Masaya, Kawana, Hiromasa, Nakagawa, Taneaki, Miyamoto, Takeshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5089792/
https://www.ncbi.nlm.nih.gov/pubmed/27802325
http://dx.doi.org/10.1371/journal.pone.0165922