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CPEB4 is regulated during cell cycle by ERK2/Cdk1-mediated phosphorylation and its assembly into liquid-like droplets

The four members of the vertebrate CPEB family of RNA-binding proteins share similar RNA-binding domains by which they regulate the translation of CPE-containing mRNAs, thereby controlling cell cycle and differentiation or synaptic plasticity. However, the N-terminal domains of CPEBs are distinct an...

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Detalles Bibliográficos
Autores principales: Guillén-Boixet, Jordina, Buzon, Víctor, Salvatella, Xavier, Méndez, Raúl
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5089860/
https://www.ncbi.nlm.nih.gov/pubmed/27802129
http://dx.doi.org/10.7554/eLife.19298