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Ongoing resolution of duplicate gene functions shapes the diversification of a metabolic network

The evolutionary mechanisms leading to duplicate gene retention are well understood, but the long-term impacts of paralog differentiation on the regulation of metabolism remain underappreciated. Here we experimentally dissect the functions of two pairs of ancient paralogs of the GALactose sugar util...

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Detalles Bibliográficos
Autores principales: Kuang, Meihua Christina, Hutchins, Paul D, Russell, Jason D, Coon, Joshua J, Hittinger, Chris Todd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5089864/
https://www.ncbi.nlm.nih.gov/pubmed/27690225
http://dx.doi.org/10.7554/eLife.19027