Neurotoxicity of the Parkinson Disease-Associated Pesticide Ziram Is Synuclein-Dependent in Zebrafish Embryos

BACKGROUND: Exposure to the commonly used dithiocarbamate (DTC) pesticides is associated with an increased risk of developing Parkinson disease (PD), although the mechanisms by which they exert their toxicity are not completely understood. OBJECTIVE: We studied the mechanisms of ziram’s (a DTC fungi...

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Detalles Bibliográficos
Autores principales: Lulla, Aaron, Barnhill, Lisa, Bitan, Gal, Ivanova, Magdalena I., Nguyen, Binh, O’Donnell, Kelley, Stahl, Mark C., Yamashiro, Chase, Klärner, Frank-Gerrit, Schrader, Thomas, Sagasti, Alvaro, Bronstein, Jeff M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Institute of Environmental Health Sciences 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5089875/
https://www.ncbi.nlm.nih.gov/pubmed/27301718
http://dx.doi.org/10.1289/EHP141

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