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Alcohol modulation of BK channel gating depends on β subunit composition
In most mammalian tissues, Ca(2+)(i)/voltage-gated, large conductance K(+) (BK) channels consist of channel-forming slo1 and auxiliary (β1–β4) subunits. When Ca(2+)(i) (3–20 µM) reaches the vicinity of BK channels and increases their activity at physiological voltages, β1- and β4-containing BK chann...
Autores principales: | Kuntamallappanavar, Guruprasad, Dopico, Alex M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5089933/ https://www.ncbi.nlm.nih.gov/pubmed/27799321 http://dx.doi.org/10.1085/jgp.201611594 |
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