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Independent activation of ion conduction pores in the double-barreled calcium-activated chloride channel TMEM16A
The TMEM16 proteins constitute a family of membrane proteins with unusual functional breadth, including lipid scramblases and Cl(−) channels. Members of both these branches are activated by Ca(2+), acting from the intracellular side, and probably share a common architecture, which was defined in the...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5089934/ https://www.ncbi.nlm.nih.gov/pubmed/27799318 http://dx.doi.org/10.1085/jgp.201611650 |