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Independent activation of distinct pores in dimeric TMEM16A channels
The TMEM16 family encompasses Ca(2+)-activated Cl(−) channels (CaCCs) and lipid scramblases. These proteins are formed by two identical subunits, as confirmed by the recently solved crystal structure of a TMEM16 lipid scramblase. However, the high-resolution structure did not provide definitive info...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5089935/ https://www.ncbi.nlm.nih.gov/pubmed/27799319 http://dx.doi.org/10.1085/jgp.201611651 |