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Complex Dynamical Behaviour in an Epidemic Model with Control

We analyse the dynamical behaviour of a simple, widely used model that integrates epidemiological dynamics with disease control and economic constraint on the control resources. We consider both the deterministic model and its stochastic counterpart. Despite its simplicity, the model exhibits mathem...

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Detalles Bibliográficos
Autores principales: Vyska, Martin, Gilligan, Christopher
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5090017/
https://www.ncbi.nlm.nih.gov/pubmed/27757705
http://dx.doi.org/10.1007/s11538-016-0217-6
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author Vyska, Martin
Gilligan, Christopher
author_facet Vyska, Martin
Gilligan, Christopher
author_sort Vyska, Martin
collection PubMed
description We analyse the dynamical behaviour of a simple, widely used model that integrates epidemiological dynamics with disease control and economic constraint on the control resources. We consider both the deterministic model and its stochastic counterpart. Despite its simplicity, the model exhibits mathematically rich dynamics, including multiple stable fixed points and stable limit cycles arising from global bifurcations. We show that the existence of the limit cycles in the deterministic model has important consequences in modelling the range of potential effects the control can have. The stochastic effects further interact with the deterministic dynamical structure by facilitating transitions between different attractors of the system. The interaction is important for the predictive power of the model and in using the model to optimize allocation when resources for control are limited. We conclude that when studying models with constrained control, special care should be given to the dynamical behaviour of the system and its interplay with stochastic effects.
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spelling pubmed-50900172016-11-17 Complex Dynamical Behaviour in an Epidemic Model with Control Vyska, Martin Gilligan, Christopher Bull Math Biol Original Article We analyse the dynamical behaviour of a simple, widely used model that integrates epidemiological dynamics with disease control and economic constraint on the control resources. We consider both the deterministic model and its stochastic counterpart. Despite its simplicity, the model exhibits mathematically rich dynamics, including multiple stable fixed points and stable limit cycles arising from global bifurcations. We show that the existence of the limit cycles in the deterministic model has important consequences in modelling the range of potential effects the control can have. The stochastic effects further interact with the deterministic dynamical structure by facilitating transitions between different attractors of the system. The interaction is important for the predictive power of the model and in using the model to optimize allocation when resources for control are limited. We conclude that when studying models with constrained control, special care should be given to the dynamical behaviour of the system and its interplay with stochastic effects. Springer US 2016-10-18 2016 /pmc/articles/PMC5090017/ /pubmed/27757705 http://dx.doi.org/10.1007/s11538-016-0217-6 Text en © The Author(s) 2016 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
spellingShingle Original Article
Vyska, Martin
Gilligan, Christopher
Complex Dynamical Behaviour in an Epidemic Model with Control
title Complex Dynamical Behaviour in an Epidemic Model with Control
title_full Complex Dynamical Behaviour in an Epidemic Model with Control
title_fullStr Complex Dynamical Behaviour in an Epidemic Model with Control
title_full_unstemmed Complex Dynamical Behaviour in an Epidemic Model with Control
title_short Complex Dynamical Behaviour in an Epidemic Model with Control
title_sort complex dynamical behaviour in an epidemic model with control
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5090017/
https://www.ncbi.nlm.nih.gov/pubmed/27757705
http://dx.doi.org/10.1007/s11538-016-0217-6
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