Unshared binding sites for Bacillus thuringiensis Cry3Aa and Cry3Ca proteins in the weevil Cylas puncticollis (Brentidae)

Bacillus thuringiensis Cry3Aa and Cry3Ca proteins have been reported to be toxic against the African sweetpotato pest Cylas puncticollis. In the present work, the binding sites of these proteins in C. puncticollis brush border vesicles suggest the occurrence of different binding sites, but only one...

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Autores principales: Hernández-Martínez, Patricia, Vera-Velasco, Natalia Mara, Escriche, Baltasar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Pergamon Press 2016
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5090047/
https://www.ncbi.nlm.nih.gov/pubmed/27662801
http://dx.doi.org/10.1016/j.toxicon.2016.09.014
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author Hernández-Martínez, Patricia
Vera-Velasco, Natalia Mara
Escriche, Baltasar
author_facet Hernández-Martínez, Patricia
Vera-Velasco, Natalia Mara
Escriche, Baltasar
author_sort Hernández-Martínez, Patricia
collection PubMed
description Bacillus thuringiensis Cry3Aa and Cry3Ca proteins have been reported to be toxic against the African sweetpotato pest Cylas puncticollis. In the present work, the binding sites of these proteins in C. puncticollis brush border vesicles suggest the occurrence of different binding sites, but only one of them is shared. Our results suggest that pest resistance mediated by alteration of the shared Cry-receptor binding site might not render both Cry proteins ineffective.
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spelling pubmed-50900472016-11-07 Unshared binding sites for Bacillus thuringiensis Cry3Aa and Cry3Ca proteins in the weevil Cylas puncticollis (Brentidae) Hernández-Martínez, Patricia Vera-Velasco, Natalia Mara Escriche, Baltasar Toxicon Short Communication Bacillus thuringiensis Cry3Aa and Cry3Ca proteins have been reported to be toxic against the African sweetpotato pest Cylas puncticollis. In the present work, the binding sites of these proteins in C. puncticollis brush border vesicles suggest the occurrence of different binding sites, but only one of them is shared. Our results suggest that pest resistance mediated by alteration of the shared Cry-receptor binding site might not render both Cry proteins ineffective. Pergamon Press 2016-11 /pmc/articles/PMC5090047/ /pubmed/27662801 http://dx.doi.org/10.1016/j.toxicon.2016.09.014 Text en © 2016 The Authors http://creativecommons.org/licenses/by/4.0/ This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Short Communication
Hernández-Martínez, Patricia
Vera-Velasco, Natalia Mara
Escriche, Baltasar
Unshared binding sites for Bacillus thuringiensis Cry3Aa and Cry3Ca proteins in the weevil Cylas puncticollis (Brentidae)
title Unshared binding sites for Bacillus thuringiensis Cry3Aa and Cry3Ca proteins in the weevil Cylas puncticollis (Brentidae)
title_full Unshared binding sites for Bacillus thuringiensis Cry3Aa and Cry3Ca proteins in the weevil Cylas puncticollis (Brentidae)
title_fullStr Unshared binding sites for Bacillus thuringiensis Cry3Aa and Cry3Ca proteins in the weevil Cylas puncticollis (Brentidae)
title_full_unstemmed Unshared binding sites for Bacillus thuringiensis Cry3Aa and Cry3Ca proteins in the weevil Cylas puncticollis (Brentidae)
title_short Unshared binding sites for Bacillus thuringiensis Cry3Aa and Cry3Ca proteins in the weevil Cylas puncticollis (Brentidae)
title_sort unshared binding sites for bacillus thuringiensis cry3aa and cry3ca proteins in the weevil cylas puncticollis (brentidae)
topic Short Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5090047/
https://www.ncbi.nlm.nih.gov/pubmed/27662801
http://dx.doi.org/10.1016/j.toxicon.2016.09.014
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AT escrichebaltasar unsharedbindingsitesforbacillusthuringiensiscry3aaandcry3caproteinsintheweevilcylaspuncticollisbrentidae

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