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High levels of HtrA4 observed in preeclamptic circulation drastically alter endothelial gene expression and induce inflammation in human umbilical vein endothelial cells

INTRODUCTION: Preeclampsia (PE) is a life-threatening pregnancy disorder characterized by wide-spread endothelial dysfunction. Placental factors circulating in the maternal blood are believed to cause endothelial dysfunction. Our previous study identified HtrA4 as a placenta-specific serine protease...

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Detalles Bibliográficos
Autores principales:	Wang, Yao, Nie, Guiying
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5090051/ https://www.ncbi.nlm.nih.gov/pubmed/27780539 http://dx.doi.org/10.1016/j.placenta.2016.09.003

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