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Tomographic docking suggests the mechanism of auxin receptor TIR1 selectivity

We study the binding of plant hormone IAA on its receptor TIR1, introducing a novel computational method that we call tomographic docking and that accounts for interactions occurring along the depth of the binding pocket. Our results suggest that selectivity is related to constraints that potential...

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Detalles Bibliográficos
Autores principales:	Uzunova, Veselina V., Quareshy, Mussa, del Genio, Charo I., Napier, Richard M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Royal Society 2016
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5090058/ https://www.ncbi.nlm.nih.gov/pubmed/27805904 http://dx.doi.org/10.1098/rsob.160139

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