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Identification of the critical residues responsible for differential reactivation of the triosephosphate isomerases of two trypanosomes

The reactivation of triosephosphate isomerase (TIM) from unfolded monomers induced by guanidine hydrochloride involves different amino acids of its sequence in different stages of protein refolding. We describe a systematic mutagenesis method to find critical residues for certain physico-chemical pr...

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Detalles Bibliográficos
Autores principales:	Rodríguez-Bolaños, Monica, Cabrera, Nallely, Perez-Montfort, Ruy
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Royal Society 2016
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5090059/ https://www.ncbi.nlm.nih.gov/pubmed/27733588 http://dx.doi.org/10.1098/rsob.160161

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