Cargando…
Analysis of Drosophila p8 and p52 mutants reveals distinct roles for the maintenance of TFIIH stability and male germ cell differentiation
Eukaryotic gene expression is activated by factors that interact within complex machinery to initiate transcription. An important component of this machinery is the DNA repair/transcription factor TFIIH. Mutations in TFIIH result in three human syndromes: xeroderma pigmentosum, Cockayne syndrome and...
Autores principales: | Cruz-Becerra, Grisel, Juárez, Mandy, Valadez-Graham, Viviana, Zurita, Mario |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5090060/ https://www.ncbi.nlm.nih.gov/pubmed/27805905 http://dx.doi.org/10.1098/rsob.160222 |
Ejemplares similares
-
TFIIH: New Discoveries Regarding its Mechanisms and Impact on Cancer Treatment
por: Zurita, Mario, et al.
Publicado: (2016) -
p8/TTDA Overexpression Enhances UV-Irradiation Resistance and Suppresses TFIIH Mutations in a Drosophila Trichothiodystrophy Model
por: Aguilar-Fuentes, Javier, et al.
Publicado: (2008) -
Drosophila as a Model Organism to Understand the Effects during Development of TFIIH-Related Human Diseases
por: Zurita, Mario, et al.
Publicado: (2020) -
Structural insight into the TFIIE–TFIIH interaction: TFIIE and p53 share the binding region on TFIIH
por: Okuda, Masahiko, et al.
Publicado: (2008) -
The TFIIH Subunit p89 (XPB) Localizes to the Centrosome during Mitosis
por: Weber, Achim, et al.
Publicado: (2010)