Reduced HMGB 1-Mediated Pathway and Oxidative Stress in Resveratrol-Treated Diabetic Mice: A Possible Mechanism of Cardioprotection of Resveratrol in Diabetes Mellitus

Myocardial fibrosis and inflammation are intricately linked in diabetic cardiomyopathy (DCM), and resveratrol has been shown to attenuate oxidative stress, inflammation, and fibrosis in several cell types or animal models. High mobility group box 1 (HMGB 1), a proinflammatory cytokine, has been repo...

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Detalles Bibliográficos
Autores principales: Wu, Han, Sheng, Zhen-Qiang, Xie, Jun, Li, Ran, Chen, Liang, Li, Guan-Nan, Wang, Lian, Xu, Biao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5090089/
https://www.ncbi.nlm.nih.gov/pubmed/27833703
http://dx.doi.org/10.1155/2016/9836860

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