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Am80‐GCSF synergizes myeloid expansion and differentiation to generate functional neutrophils that reduce neutropenia‐associated infection and mortality

Neutrophils generated by granulocyte colony‐stimulating factor (GCSF) are functionally immature and, consequently, cannot effectively reduce infection and infection‐related mortality in cancer chemotherapy‐induced neutropenia (CCIN). Am80, a retinoic acid (RA) agonist that enhances granulocytic diff...

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Detalles Bibliográficos
Autores principales: Li, Lin, Qi, Xiaotian, Sun, Weili, Abdel‐Azim, Hisham, Lou, Siyue, Zhu, Hong, Prasadarao, Nemani V, Zhou, Alice, Shimada, Hiroyuki, Shudo, Koichi, Kim, Yong‐Mi, Khazal, Sajad, He, Qiaojun, Warburton, David, Wu, Lingtao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5090663/
https://www.ncbi.nlm.nih.gov/pubmed/27737899
http://dx.doi.org/10.15252/emmm.201606434