Manipulation of cell membrane using carbon nanotube scaffold as a photoresponsive stimuli generator

We describe, for the first time, the perforation of the cell membrane in the targeted single cell based on the nanosecond pulsed near-infrared (NIR) laser irradiation of a thin film of carbon nanotubes that act as an effective photon absorber as well as stimuli generator. When the power of NIR laser...

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Detalles Bibliográficos
Autores principales: Sada, Takao, Fujigaya, Tsuyohiko, Nakashima, Naotoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2014
Materias:
Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5090691/
https://www.ncbi.nlm.nih.gov/pubmed/27877703
http://dx.doi.org/10.1088/1468-6996/15/4/045002
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author Sada, Takao
Fujigaya, Tsuyohiko
Nakashima, Naotoshi
author_facet Sada, Takao
Fujigaya, Tsuyohiko
Nakashima, Naotoshi
author_sort Sada, Takao
collection PubMed
description We describe, for the first time, the perforation of the cell membrane in the targeted single cell based on the nanosecond pulsed near-infrared (NIR) laser irradiation of a thin film of carbon nanotubes that act as an effective photon absorber as well as stimuli generator. When the power of NIR laser is over 17.5 μJ/pulse, the cell membrane after irradiation is irreversibly disrupted and results in cell death. In sharp contrast, the perforation of the cell membrane occurs at suitable laser power (∼15 μJ/pulse) without involving cell termination.
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spelling pubmed-50906912016-11-22 Manipulation of cell membrane using carbon nanotube scaffold as a photoresponsive stimuli generator Sada, Takao Fujigaya, Tsuyohiko Nakashima, Naotoshi Sci Technol Adv Mater Papers We describe, for the first time, the perforation of the cell membrane in the targeted single cell based on the nanosecond pulsed near-infrared (NIR) laser irradiation of a thin film of carbon nanotubes that act as an effective photon absorber as well as stimuli generator. When the power of NIR laser is over 17.5 μJ/pulse, the cell membrane after irradiation is irreversibly disrupted and results in cell death. In sharp contrast, the perforation of the cell membrane occurs at suitable laser power (∼15 μJ/pulse) without involving cell termination. Taylor & Francis 2014-07-07 /pmc/articles/PMC5090691/ /pubmed/27877703 http://dx.doi.org/10.1088/1468-6996/15/4/045002 Text en © 2014 National Institute for Materials Science http://creativecommons.org/licenses/by/3.0/ Content from this work may be used under the terms of the Creative Commons Attribution 3.0 licence (http://creativecommons.org/licenses/by/3.0) . Any further distribution of this work must maintain attribution to the author(s) and the title of the work, journal citation and DOI.
spellingShingle Papers
Sada, Takao
Fujigaya, Tsuyohiko
Nakashima, Naotoshi
Manipulation of cell membrane using carbon nanotube scaffold as a photoresponsive stimuli generator
title Manipulation of cell membrane using carbon nanotube scaffold as a photoresponsive stimuli generator
title_full Manipulation of cell membrane using carbon nanotube scaffold as a photoresponsive stimuli generator
title_fullStr Manipulation of cell membrane using carbon nanotube scaffold as a photoresponsive stimuli generator
title_full_unstemmed Manipulation of cell membrane using carbon nanotube scaffold as a photoresponsive stimuli generator
title_short Manipulation of cell membrane using carbon nanotube scaffold as a photoresponsive stimuli generator
title_sort manipulation of cell membrane using carbon nanotube scaffold as a photoresponsive stimuli generator
topic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5090691/
https://www.ncbi.nlm.nih.gov/pubmed/27877703
http://dx.doi.org/10.1088/1468-6996/15/4/045002
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AT nakashimanaotoshi manipulationofcellmembraneusingcarbonnanotubescaffoldasaphotoresponsivestimuligenerator

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