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Persisting neurobehavioral effects of developmental copper exposure in wildtype and metallothionein 1 and 2 knockout mice

BACKGROUND: Metallothioneins (MT) are small proteins, which are crucial for the distribution of heavy and transition metals. Previously, we found in mice that knockout of MT 1 and 2 genes (MTKO) impaired spatial learning and potentiated the learning impairment caused by developmental mercury exposur...

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Detalles Bibliográficos
Autores principales: Petro, Ann, Sexton, Hannah G., Miranda, Caroline, Rastogi, Anit, Freedman, Jonathan H., Levin, Edward D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5090947/
https://www.ncbi.nlm.nih.gov/pubmed/27802831
http://dx.doi.org/10.1186/s40360-016-0096-3