Fxyd2 regulates Aδ- and C-fiber mechanosensitivity and is required for the maintenance of neuropathic pain

Identification of the molecular mechanisms governing sensory neuron subtype excitability is a key requisite for the development of treatments for somatic sensory disorders. Here, we show that the Na,K-ATPase modulator Fxyd2 is specifically required for setting the mechanosensitivity of Aδ-fiber low-...

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Detalles Bibliográficos
Autores principales: Ventéo, Stéphanie, Laffray, Sophie, Wetzel, Christiane, Rivat, Cyril, Scamps, Frédérique, Méchaly, Ilana, Bauchet, Luc, Raoul, Cédric, Bourinet, Emmanuel, Lewin, Gary R., Carroll, Patrick, Pattyn, Alexandre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5090990/
https://www.ncbi.nlm.nih.gov/pubmed/27805035
http://dx.doi.org/10.1038/srep36407

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