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The morphological and functional effects of exercise in the aquatic environment, performed before and/or after sciatic nerve compression in Wistar rats

The aim of this study was to evaluate the effects of exercise in the aquatic environment, performed before and/or after sciatic nerve compression in Wistar rats on morphological and functional parameters. Twenty-five Wistar rats were divided into the following groups: control (C), lesion (L), traine...

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Autores principales: Kakihata, Camila Mayumi Martin, Malanotte, Jéssica Aline, Karvat, Jhenifer, Brancalhão, Rose Meire Costa, de Fátima Chasko Ribeiro, Lucinéia, Bertolini, Gladson Ricardo Flor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society of Exercise Rehabilitation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5091053/
https://www.ncbi.nlm.nih.gov/pubmed/27807516
http://dx.doi.org/10.12965/jer.1632670.335
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author Kakihata, Camila Mayumi Martin
Malanotte, Jéssica Aline
Karvat, Jhenifer
Brancalhão, Rose Meire Costa
de Fátima Chasko Ribeiro, Lucinéia
Bertolini, Gladson Ricardo Flor
author_facet Kakihata, Camila Mayumi Martin
Malanotte, Jéssica Aline
Karvat, Jhenifer
Brancalhão, Rose Meire Costa
de Fátima Chasko Ribeiro, Lucinéia
Bertolini, Gladson Ricardo Flor
author_sort Kakihata, Camila Mayumi Martin
collection PubMed
description The aim of this study was to evaluate the effects of exercise in the aquatic environment, performed before and/or after sciatic nerve compression in Wistar rats on morphological and functional parameters. Twenty-five Wistar rats were divided into the following groups: control (C), lesion (L), trained+lesion (TL), lesion+exercise (LE), and training+lesion+exercise (TLE), who underwent right sciatic nerve compression on day 21 of the experiment. The TL and TLE groups were submitted to a jumping exercise in a water environment for 20 days prior to injury and the LE and TLE groups after injury. The functional analysis was carried out using the sciatic functional index (SFI). On the last day of the experiment, the right sciatic nerves were collected, processed and analysed according to morphology and morphometry. The C group showed higher SFI in relation to the other groups. In the morphometric analysis, in comparison to C, all groups showed a decrease in the diameter of the injured nerve fibre, the myelin sheath and an increase in the percentage of connective tissue. There was a decrease in axon diameter in L, TL, and LE groups and a decrease in the density of nerve fibres in the TL and LE groups. The exercise did not affect functional recovery. However, the exercise prior to the injury improved morphology of the nervous tissue, and when performed pre- and postinjury, there was also an improvement in nerve regeneration, but this was not the case with exercise performed after the injury demonstrating worse results.
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spelling pubmed-50910532016-11-02 The morphological and functional effects of exercise in the aquatic environment, performed before and/or after sciatic nerve compression in Wistar rats Kakihata, Camila Mayumi Martin Malanotte, Jéssica Aline Karvat, Jhenifer Brancalhão, Rose Meire Costa de Fátima Chasko Ribeiro, Lucinéia Bertolini, Gladson Ricardo Flor J Exerc Rehabil Original Article The aim of this study was to evaluate the effects of exercise in the aquatic environment, performed before and/or after sciatic nerve compression in Wistar rats on morphological and functional parameters. Twenty-five Wistar rats were divided into the following groups: control (C), lesion (L), trained+lesion (TL), lesion+exercise (LE), and training+lesion+exercise (TLE), who underwent right sciatic nerve compression on day 21 of the experiment. The TL and TLE groups were submitted to a jumping exercise in a water environment for 20 days prior to injury and the LE and TLE groups after injury. The functional analysis was carried out using the sciatic functional index (SFI). On the last day of the experiment, the right sciatic nerves were collected, processed and analysed according to morphology and morphometry. The C group showed higher SFI in relation to the other groups. In the morphometric analysis, in comparison to C, all groups showed a decrease in the diameter of the injured nerve fibre, the myelin sheath and an increase in the percentage of connective tissue. There was a decrease in axon diameter in L, TL, and LE groups and a decrease in the density of nerve fibres in the TL and LE groups. The exercise did not affect functional recovery. However, the exercise prior to the injury improved morphology of the nervous tissue, and when performed pre- and postinjury, there was also an improvement in nerve regeneration, but this was not the case with exercise performed after the injury demonstrating worse results. Korean Society of Exercise Rehabilitation 2016-10-31 /pmc/articles/PMC5091053/ /pubmed/27807516 http://dx.doi.org/10.12965/jer.1632670.335 Text en Copyright © 2016 Korean Society of Exercise Rehabilitation This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Kakihata, Camila Mayumi Martin
Malanotte, Jéssica Aline
Karvat, Jhenifer
Brancalhão, Rose Meire Costa
de Fátima Chasko Ribeiro, Lucinéia
Bertolini, Gladson Ricardo Flor
The morphological and functional effects of exercise in the aquatic environment, performed before and/or after sciatic nerve compression in Wistar rats
title The morphological and functional effects of exercise in the aquatic environment, performed before and/or after sciatic nerve compression in Wistar rats
title_full The morphological and functional effects of exercise in the aquatic environment, performed before and/or after sciatic nerve compression in Wistar rats
title_fullStr The morphological and functional effects of exercise in the aquatic environment, performed before and/or after sciatic nerve compression in Wistar rats
title_full_unstemmed The morphological and functional effects of exercise in the aquatic environment, performed before and/or after sciatic nerve compression in Wistar rats
title_short The morphological and functional effects of exercise in the aquatic environment, performed before and/or after sciatic nerve compression in Wistar rats
title_sort morphological and functional effects of exercise in the aquatic environment, performed before and/or after sciatic nerve compression in wistar rats
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5091053/
https://www.ncbi.nlm.nih.gov/pubmed/27807516
http://dx.doi.org/10.12965/jer.1632670.335
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