Transcriptional Activation of Pericentromeric Satellite Repeats and Disruption of Centromeric Clustering upon Proteasome Inhibition

Heterochromatinisation of pericentromeres, which in mice consist of arrays of major satellite repeats, are important for centromere formation and maintenance of genome stability. The dysregulation of this process has been linked to genomic stress and various cancers. Here we show in mice that the pr...

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Detalles Bibliográficos
Autores principales: Natisvili, Theona, Yandim, Cihangir, Silva, Raquel, Emanuelli, Giulia, Krueger, Felix, Nageshwaran, Sathiji, Festenstein, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5091837/
https://www.ncbi.nlm.nih.gov/pubmed/27806100
http://dx.doi.org/10.1371/journal.pone.0165873

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