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Cycloheximide Can Induce Bax/Bak Dependent Myeloid Cell Death Independently of Multiple BH3-Only Proteins

Apoptosis mediated by Bax or Bak is usually thought to be triggered by BH3-only members of the Bcl-2 protein family. BH3-only proteins can directly bind to and activate Bax or Bak, or indirectly activate them by binding to anti-apoptotic Bcl-2 family members, thereby relieving their inhibition of Ba...

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Detalles Bibliográficos
Autores principales:	Goodall, Katharine J., Finch-Edmondson, Megan L., van Vuuren, Joanne, Yeoh, George C., Gentle, Ian E., Vince, James E., Ekert, Paul G., Vaux, David L., Callus, Bernard A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5091851/ https://www.ncbi.nlm.nih.gov/pubmed/27806040 http://dx.doi.org/10.1371/journal.pone.0164003

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