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In Vitro and In Vivo Antitumor Activity of [Pt(O,O′-acac)(γ-acac)(DMS)] in Malignant Pleural Mesothelioma

Malignant pleural mesothelioma (MPM) is an aggressive malignancy highly resistant to chemotherapy. There is an urgent need for effective therapy inasmuch as resistance, intrinsic and acquired, to conventional therapies is common. Among Pt(II) antitumor drugs, [Pt(O,O′-acac)(γ-acac)(DMS)] (Ptac2S) ha...

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Detalles Bibliográficos
Autores principales: Muscella, Antonella, Vetrugno, Carla, Cossa, Luca Giulio, Antonaci, Giovanna, De Nuccio, Francesco, De Pascali, Sandra Angelica, Fanizzi, Francesco Paolo, Marsigliante, Santo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5091852/
https://www.ncbi.nlm.nih.gov/pubmed/27806086
http://dx.doi.org/10.1371/journal.pone.0165154