Intracellular Iron Chelation Modulates the Macrophage Iron Phenotype with Consequences on Tumor Progression

A growing body of evidence suggests that macrophage polarization dictates the expression of iron-regulated genes. Polarization towards iron sequestration depletes the microenvironment, whereby extracellular pathogen growth is limited and inflammation is fostered. In contrast, iron release contribute...

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Detalles Bibliográficos
Autores principales: Mertens, Christina, Akam, Eman Abureida, Rehwald, Claudia, Brüne, Bernhard, Tomat, Elisa, Jung, Michaela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5091876/
https://www.ncbi.nlm.nih.gov/pubmed/27806101
http://dx.doi.org/10.1371/journal.pone.0166164

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5091876/
https://www.ncbi.nlm.nih.gov/pubmed/27806101
http://dx.doi.org/10.1371/journal.pone.0166164

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