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Intracellular Iron Chelation Modulates the Macrophage Iron Phenotype with Consequences on Tumor Progression
A growing body of evidence suggests that macrophage polarization dictates the expression of iron-regulated genes. Polarization towards iron sequestration depletes the microenvironment, whereby extracellular pathogen growth is limited and inflammation is fostered. In contrast, iron release contribute...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5091876/ https://www.ncbi.nlm.nih.gov/pubmed/27806101 http://dx.doi.org/10.1371/journal.pone.0166164 |