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Atomic mutagenesis in ion channels with engineered stoichiometry

C-type inactivation of potassium channels fine-tunes the electrical signaling in excitable cells through an internal timing mechanism that is mediated by a hydrogen bond network in the channels' selectively filter. Previously, we used nonsense suppression to highlight the role of the conserved...

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Detalles Bibliográficos
Autores principales:	Lueck, John D, Mackey, Adam L, Infield, Daniel T, Galpin, Jason D, Li, Jing, Roux, Benoît, Ahern, Christopher A
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2016
Materias:	Biochemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5092047/ https://www.ncbi.nlm.nih.gov/pubmed/27710770 http://dx.doi.org/10.7554/eLife.18976

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