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The ubiquitin-proteasome system regulates focal adhesions at the leading edge of migrating cells

Cell migration requires the cyclical assembly and disassembly of focal adhesions. Adhesion induces phosphorylation of focal adhesion proteins, including Cas (Crk-associated substrate/p130Cas/BCAR1). However, Cas phosphorylation stimulates adhesion turnover. This raises the question of how adhesion a...

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Detalles Bibliográficos
Autores principales:	Teckchandani, Anjali, Cooper, Jonathan A
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2016
Materias:	Cell Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5092051/ https://www.ncbi.nlm.nih.gov/pubmed/27656905 http://dx.doi.org/10.7554/eLife.17440

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